Abstract
Throughout history, medicinal plants have been utilized, laying the foundation for contemporary medicine. Plant-derived compounds have been a vital source for developing medications. Colocasia esculenta stands out among traditional crops for its significant nutritional and medicinal potential, surpassing many other tuber crops. In this study, the antioxidant, mutagenicity, and antimutagenicity of four different extracts (hexane, acetone, methanol, and aqueous) of C. esculenta were investigated. Antioxidant activities of C. esculenta extracts were detected with the determination of total phenolic/flavonoid content (TPC/TFC), total antioxidant activity (TAC), and DPPH free radical scavenging activity. Acetone extract of C. esculenta exhibited the highest values in all TPC, TFC, TAC, and the DPPH free radical scavenging analyses. The mutagenic and antimutagenic activities of those four extracts were examined with TA98 and TA100 strains of Salmonella typhimurium. In higher concentrations, acetone and methanol extracts showed stronger mutagenic activity than the other extracts in both strains. The highest antimutagenic activity was observed in hexane and acetone in strain TA98.
| Keywords: | Colocasia esculenta Antioxidant Activity Mutagenic Antimutagenic |